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CAF-derived exosomes have been shown to contain amino acids, lipids and TCA intermediates that inhibit mitochondrial oxidative phosphorylation, thereby increasing glutamine-dependent reductive carboxylation and promote glycolysis in tumor cells [149]

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[DOI] [PubMed] [Google Scholar] Lang CA, Naryshkin S, Schneider DL, Mills BJ, Lindeman RD